Drug discovery platform
The drug discovery platform combines a liquid handling system (Sciclone), bioimager (ImageXpress), zebrafish environment system, multiwell plate washer, and embryo biosorter allowing drug screening in zebrafish larvae. We perform drug safety profiles, pharmacology assays, behavioral assays in various disease models.
Zebrafish holding facility
The zebrafish holding facility includes 30 transgenic zebrafish lines, 5 different wild-type lines, and over 1,500 tanks. It uses state-of-the-art aquatic systems for optimal care including rich diet of brine shrimp, rotifers, and supplements. Water quality and husbandry are our main priorities to rear healthy zebrafish.
The research platform designs experimental protocols and performs research projects using fluorescent microscopy in reporter lines, behavioral, respiratory, cardiovascular assays.
We specialize in neuroscience research but are open to all relevant diseases.
Gene editing platform
The gene editing platform allows development of transgenic reporter and knockout lines allowing the study of various diseases. We use CRISPR-Cas9, produce plasmids, perform egg microinjection, morpholino oligonucleotides and perform genotyping and sequencing.