Water Drops


We approach science with integrity, innovation and passion, and thrive to find concrete solutions to complex health issues!


Gaspard Montandon, PhD


Phone: 416-864-5924

Gaspard Montandon is the director of flow and a scientist at Unity Health Toronto. His expertise covers neuroscience, respiratory physiology, opioid research, and zebrafish drug discovery



Yara Zayed, PhD


Phone: 416-864-6060 x 77664

Yara Zayed is the research manager of flow. Her expertise includes gene editing, molecule biology, and zebrafish maintenance and care. 


Antonio Mauro, PhD


Phone: 416-864-6060 x 77664


Carolina Scarpellini, PhD


Phone: 416-864-6060 x 77664

Antonio Mauro is a research technician with expertise in drug discovery and cardiovascular diseases. 

Carolina Scarpellini is a research technician expert in animal physiology and neuroscience. 


Sonia Aksamit, MSc


Phone: 416-864-6060 x 77664


Patricia Barbalho, PhD


Phone: 416-864-6060 x 77664

Sonia Aksamit is a research technician at flow. Her expertise covers zebrafish and molecular genetics and she studied the molecular mechanisms of idiopathic scoliosis using zebrafish. 

Patricia Barbalho is a postdoctoral fellow at flow. Her expertise covers zebrafish models of epilepsy and neurodevelopment disorders in knockout zebrafish.

Publications from team members:

- Respiratory depression and analgesia by opioid drugs in freely-behaving larval zebrafish. Zaig S, Scarpellini C,    Montandon G. eLife. 2021. 

Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. Lin SJ, Vona B, Barbalho PG, et al., Genet Med. 2021 Oct;23(10):1933-1943.

- Nodal regulates ovarian functions in zebrafish. Zayed Y, Malik R, Qi X, Peng C. Mol Cell Endocrinol. 2020. 

- Identification of Novel MicroRNAs and Characterization of MicroRNA Expression Profiles in Zebrafish Ovarian

  Follicular Cells. Zayed Y, Qi X, Peng C. Front Endocrinol (Lausanne). 2019.

- Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation. O'Brien J, Hayder H, Zayed Y, Peng C. 

  Front Endocrinol (Lausanne). 2018 Aug 3;9:402.

- Development of a zebrafish sepsis model for high-throughput drug discovery. Philip AM, Wang Y, Mauro A, El-Rass S,

  Marshall JC, Lee WL, Slutsky AS, dosSantos CC, Wen XY. Mol Med. 2017.

- Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish. Mauro A, Ng R,

  Li JY, Guan R, Wang Y, Singh KK, Wen XY. PLOS One. 2017.

- Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly. El-Rass S, Eisa-Beygi

  S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY. Biology Open. 2017.


- Cyclooxygenase-1 as a Potential Therapeutic Target for Seizure Suppression: Evidences from Zebrafish Pentylenetetrazole-Seizure Model. Barbalho PG, Carvalho BS, Lopes-Cendes I, Maurer-Morelli CV.

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